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What should I do if the endometrium becomes inflamed before test tube transplantation?

2024-08-10

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Inflammation of the endometrium is called endometritis. Endometritis is divided into chronic endometritis and acute endometritis. Its manifestations are as follows:

1. Chronic endometritis often presents with symptoms such as chronic abdominal pain, menorrhagia and dysmenorrhea;

2. Acute endometritis can cause increased vaginal discharge, lower abdominal pain, and even fever or bloody vaginal discharge.

If a female friend has the above symptoms, it is recommended to see a doctor in time and diagnose through gynecological examination. If it has been clearly diagnosed as endometritis, early diagnosis and treatment is the best.

Endometritis, can IVF transplantation be successful?

The endometrium is the site where the embryo implants after transplantation. If the endometrium is severely inflamed, it will affect the normal implantation of the embryo after transplantation. Therefore, female friends who are generally diagnosed with endometritis should undergo intervention treatment before arranging the next step of assisted reproductive treatment.

After diagnostic curettage or hysteroscopy, the endometrium is taken for histopathological examination. After HE staining of the endometrial tissue, the discovery of "plasma cells" in the endometrial stroma is the gold standard for diagnosing CE. However, plasma cells are difficult to identify, and at different stages, mononuclear cell infiltration and proliferating stromal cells will appear in the endometrial tissue, which are interfering cells similar to plasma cells and will interfere with the diagnosis of CE.

However, endometritis can be diagnosed through CD138 examination, which is a specific indicator of plasma cells. The endometrium can be stained specifically with CD138 by immunohistochemistry, which can more directly reflect the presence of plasma cells and exclude interfering cells.

How can we better intervene and treat endometrial inflammation when preparing for IVF?

1. Pay attention to personal hygiene at ordinary times.

2. Avoid unclean sexual life and try to avoid having sex during menstruation; do relevant care in daily life.

3. Minimize gynecological surgery to avoid damage to the cervix and vagina and infection.