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shanghai sixth hospital and tsinghua university jointly published a paper: millimeter-wave radar technology helps sleep apnea diagnosis

2024-09-19

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recently, the chinese journal of otolaryngology and head and neck surgery published a paper titled "new radar equipment for diagnosing obstructive sleep apnea: a parallel control study to evaluate equivalence with polysomnography". the study was jointly completed by the team of yin shankai, president of shanghai sixth people's hospital, and the team of li gang, professor of the department of electronic engineering at tsinghua university. it aims to study the equivalence of the millimeter-wave radar low-load sleep monitoring system qsa600 developed by qinglei technology and the traditional psg polysomnography equipment in diagnosing obstructive sleep apnea (osa). the results of the study showed that "as a new low-load sleep monitoring system, qsa600 showed a high consistency with psg in diagnosing osa and grading osa of different severities, and has good prospects for clinical application."

screenshot of the paper

the study recruited a total of 155 subjects from july to september 2023, and conducted a parallel controlled trial of qsa600 and psg in the sleep laboratory of otolaryngology and head and neck surgery, shanghai sixth people's hospital. the study used the sleep apnea-hypopnea index (ahi), a key diagnostic indicator of obstructive sleep apnea, as the main comparative data for analysis.

gcp trial site at shanghai sixth hospital

the results showed that the sensitivity of ahi 5 times/h, 15 times/h, and 30 times/h for the diagnosis of mild, moderate, and severe osa were 88.68%, 89.83%, and 97.06%, respectively, and the specificity was 94.87%, 98.84%, and 99.10%, respectively. the area under the receiver operating characteristic (roc) curve was 0.9734, 0.9909, and 0.9995, respectively. the pearson correlation between the two was 0.9872 (p<0.001); the mean difference of the bland-altman test between the two was -1.43 times/h [95% confidence interval (ci) was -8.74-5.88]; the icc between the two was 0.9850 (95% ci was 0.9754-0.9904), and a total of 94.48% (137/145) of the data fell within the consistency limit.

obstructive sleep apnea (osa) is a common sleep breathing disorder and an independent risk factor for systemic damage such as cardiovascular, metabolic, and neurodegenerative diseases. compared with the general population, osa patients have a significantly increased risk of all-cause mortality. despite the huge harm of osa, it is still not fully understood and diagnosed. it is estimated that up to 90% of osa patients are not diagnosed. millimeter-wave radar non-contact sleep monitoring products are expected to be used on a large scale in the clinical diagnosis, treatment follow-up, and epidemiological research of osa in the future, further promoting early sleep screening for the general public, moving the prevention and treatment of osa forward, and increasing the popularity of osa diagnostic services.

recently, the china association for academic degrees and graduate education released the "introduction to graduate teaching disciplines and basic degree requirements (trial version)", in which sleep medicine was listed as an independent third-level discipline under internal medicine (second-level discipline) for the first time, alongside traditional third-level disciplines such as cardiovascular disease, respiratory medicine, and critical care medicine. this marks the official recognition of sleep medicine as an independent discipline. the application of innovative medical devices that combine new millimeter-wave radar sensors with artificial intelligence technology in clinical and scientific research will also help the development of sleep medicine.