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looking back at the long river of history, there are always some key time nodes, key things stirring in them, pushing the wheel of history forward. opening the epic masterpiece of traditional chinese medicine, in the hinterland of funiu mountain in the central plains, traditional chinese medicine is blooming with increasingly bright vitality and light. with inheritance and innovation as its wings, zhongjing wanxi pharmaceutical is striving to create a new engine of new quality productivity, turning the spirit of the medical saint into a new practice of inheritance, innovation and high-quality development.

driven by innovation

innovation is the main theme of high-quality development, the leading force of new quality productivity, and the eternal theme of the development of the pharmaceutical industry. "for traditional chinese medicine, this proposition is particularly challenging. how to handle the relationship between inheritance and innovation, and how to explain the efficacy of traditional chinese medicine clearly are major tests." the person in charge of zhongjing wanxi pharmaceutical said that in order to do a good job in product innovation, the company has invested huge manpower and material resources, starting from technical research, development of classic prescriptions, and basic research, and has firmly raised the innovation banner of wan medicine.

in 2022, zhongjing wanxi pharmaceutical, as the responsible unit of the project, will launch the "research and application of key technologies for the whole industrial chain of authentic wan medicine" project, a major scientific and technological project in henan province, relying on existing research data and resources. this project considers the entire industrial chain and the entire life cycle of drug research and development as a whole, and tackles key technical difficulties one by one. in terms of variety breeding technology, the company and the henan academy of agricultural sciences jointly tackled the problem, and successively identified and cultivated new varieties such as artemisia-zheng ai 14, cornus-wanhong no. 1, and nanzhao xinyi no. 1, no. 2, and no. 3, which have the characteristics of large fruits, strong resistance, high yield, strong growth potential, and strong comprehensive disease resistance. the highest increase in yield over the control product is 37.94%, which is extremely significant. up to now, the overall project has been completed by nearly 80%, and a large number of achievements have been formed, such as the cultivation of new varieties of medicinal materials, the construction of standardized demonstration bases, the development of medical institution preparations, big health products, and the formulation of provincial standards for chinese medicine formula granules.

relying on strong basic research and unique advantages of traditional chinese medicine culture, the company's new drug research and development capabilities are also constantly strengthening, and new breakthroughs have been made in the transformation of ancient classic prescriptions. the person in charge of the company's r&d center introduced that based on the completion of the research on the classic prescription loquat qingfei granules, the company is preparing to start research on two more classic prescriptions this year. one is from zhang zhongjing's book "golden chamber synopsis", which has the effects of warming the middle and dispersing cold, replenishing deficiency and relieving pain; the other is from li dongyuan's book "orchid chamber secret collection", one of the four great masters of the jin and yuan dynasties, which has the effects of nourishing yin and purging fire, consolidating the surface and stopping sweating.

in addition, zhongjing wanxi pharmaceutical's new drug research is progressing smoothly, and the phase iii clinical study of yinao jieyu granules is being actively promoted. the new therapeutic effect of zuogui pills based on real-world data research, the mechanism of tianzhi granules and yege pills based on animal experimental research, and the disease efficacy judgment and other secondary development projects of major chinese medicine varieties are progressing smoothly. the company has achieved a comprehensive layout in the directions of innovative chinese medicines, classic formula compound preparations, and secondary development of major varieties.

digital empowerment upgrade

walking into the production workshop of zhongjing wanxi pharmaceutical, a whole row of modern production equipment comes into view, and there is almost no trace of manual operation. if it were not for the aroma of traditional chinese medicine wafting from time to time, it would be hard to believe that this is a traditional chinese medicine company. "new quality productivity is characterized by high technology, high efficiency, and high quality. compared with traditional productivity, it has achieved a transformation and leap in the quality of productivity and the creation of new value. for the pharmaceutical industry, digitalization, informatization, and intelligence are important means to create new quality productivity, which will help to achieve a dual improvement in quantity and quality." the person in charge of zhongjing wanxi pharmaceutical production told reporters.

in recent years, zhongjing wanxi pharmaceutical has adhered to the digital empowerment development strategy to comprehensively improve the digital and intelligent development level of the enterprise. in terms of information management, the company has newly launched the kingdee system, enabled the yunxinghan workflow, and used the mobile office collaborative management platform (oa). the company's information processing efficiency has increased by 60%, the dataization rate of production and operation management business has reached more than 98%, and the office automation efficiency has reached more than 90%, achieving business digitization, online process, and mobile approval.

in terms of intelligent production and manufacturing, the company has newly put into production an intelligent production line for refined pills, upgraded the mechanical counting to electronic counting, and installed new robot automatic packing equipment. this production line has passed the gmp compliance inspection of the henan provincial food and drug administration and was put into production in july 2023. it is mainly used for the production of liuwei dihuang pills and xiaoyao pills. "after the transformation and upgrading, the microwave drying process has achieved variable frequency regulation, the power of a single unit has increased from 72kw to 197kw, the production efficiency has increased from 90 bottles/minute to 160 bottles/minute, the labeling deviation has decreased from ±1.5mm to ±0.5mm, and the packing rate has increased from 90 bottles/minute to 160 bottles/minute." the person in charge of the above-mentioned production happily told reporters. "

we need to empower information technology and put into practice the promise of "putting our ancestors at ease", "putting old chinese medicine practitioners at ease", and "putting the people at ease", so that consumers can see and touch the safety and quality of medicines. "the person in charge of zhongjing wanxi pharmaceutical said that in the future, the company will further promote the combination of zhongjing culture and modern technology, launch virtual brand spokespersons, and let traditional chinese medicine and information technology collide to create more wonderful chapters.

an open attitude embraces modernity

traditional chinese medicine is a treasure of chinese civilization and a beautiful name card of chinese culture. "promoting the modernization of traditional chinese medicine is the historical mission given to traditional chinese medicine practitioners by the times, the historical responsibility of a leading traditional chinese medicine enterprise, and the inevitable requirement for creating new quality productivity of traditional chinese medicine." the person in charge of zhongjing wanxi pharmaceutical said that the company has achieved modern management of the entire life cycle of traditional chinese medicine by laying out a complete traceability system for traditional chinese medicine.

it is reported that the traceability system of zhongjing wanxi pharmaceutical is designed in accordance with the requirements of the good manufacturing practice for chinese medicinal materials (gap), which fully complies with national policy requirements. at the same time, the wechat applet tool is fully utilized, and all on-site management is realized through mobile office on the mobile phone. the image and environmental data of the production site are collected in real time through the internet of things, achieving the effect of objective data collection and visual display, helping the company to extend the drug quality supervision system to the fields, greatly ensuring the quality of drugs from the source. at present, the company has achieved full traceability and management of major raw medicinal materials such as cornus officinalis, peony, and rehmannia glutinosa, and through the company's app "zhongjing medicine knows", the traceability management data of the base is displayed to members and consumers, and the on-site internet of things real scene is visualized and broadcast live.

at the same time, zhongjing wanxi pharmaceutical began to promote the quality traceability of chinese herbal medicine slices, formula granules and chinese patent medicine liuwei dihuang pills from 2020 to 2021. the system realizes the automatic capture of quality traceability data by connecting to the enterprise erp, wms, mes and chinese herbal medicine base management platform and other business management systems, ensuring the objective authenticity of quality data collection; by improving the packaging coding line, the one-to-one coding management and traceability of chinese medicine are realized; among them, chinese herbal medicine slices and formula granules realize the quality traceability and traceability code scanning query of all varieties; in addition, for the chinese patent medicine liuwei dihuang pills, the traceability system innovatively realizes seamless connection with the original drug supervision code, and realizes the one-to-one code traceability query of the finished medicine based on the drug supervision code through the "zhongjing medicine know" app and the "zhongjing health" wechat public account.

standardization of traditional chinese medicine is a prerequisite for the modernization and internationalization of traditional chinese medicine. with the experience accumulated from "standardization construction of liuwei dihuang pills" and "transformation of modern technology platform for liuwei dihuang concentrated pills", the company has continuously revised and improved the quality standards of products such as liuwei dihuang pills and xiaoyao pills, formulated industry norms, and transformed and upgraded production equipment; at the same time, a scientific and visual full-process quality traceability system for chinese patent medicines has been formed to ensure the high-quality production and supply of products. in the future, zhongjing wanxi pharmaceutical will continue to increase investment in scientific research, dig deep into the connotation of product quality, refine the standards of product raw materials, intermediates, etc., explore and improve the product quality indicator system, and further clarify the product application market. at the same time, with the help of digital and intelligent technical equipment, a green production workshop that meets modern requirements will be built to produce high-quality chinese patent medicine products with uniform quality and consistency between batches to serve clinicians and consumers.