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how long after syphilis is cured can i prepare for pregnancy?

although pregnancy has little effect on the course of syphilis, syphilis is a serious hazard to pregnancy. treponema pallidum can be transmitted to the fetus through the placenta, causing fetal intrauterine infection, and ultimately leading to miscarriage, stillbirth, premature birth, low birth weight, congenital syphilis, etc., which greatly threatens the health of mother and child. therefore, it is very important to conduct syphilis serological tests before pregnancy to give birth to a healthy baby.

women with syphilis should be followed up regularly for 2 to 3 years after adequate anti-syphilis treatment, with a review every 3 months in the first year and every 6 months thereafter. late syphilis may require longer follow-up. if the rpr titer remains negative or remains at a low titer level for a long time, you can prepare for pregnancy under the guidance of a professional doctor. if the rpr titer turns from negative to positive or the titer increases by more than 4 times during the review, it is a serological relapse and should be retreated and anti-syphilis treatment should be performed again. after the rpr turns negative or stabilizes after treatment, you can prepare for pregnancy. during pregnancy, pregnant women need to regularly test the syphilis titer to determine whether the disease has recurred. it is recommended that pregnant women regularly review the syphilis nonspecific antibody titer every 1-2 months, and test the neonatal syphilis antibodies and titers after the fetus is delivered to determine whether preventive treatment is needed for the newborn.

for male syphilis patients, it is not recommended to prepare for pregnancy within three months of medication treatment to prevent the drugs from affecting the growth and development of the fetus. for virus carriers, since the virus exists in the seminal plasma, sperm washing can be used to obtain healthy sperm and then the female can undergo in vitro fertilization. the healthiest embryos can be selected for transplantation through the third-generation in vitro fertilization technology (pre-embryo implantation genetic diagnosis), thereby increasing the chances of pregnancy and the birth of a healthy baby.