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Will hepatitis B recur after clinical cure?

2024-07-22

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In the field of hepatitis B treatment, clinical cure is the dream goal of many patients. When patients finally achieve clinical cure after going through hardships, they will inevitably have a worry in their hearts: Will hepatitis B relapse after clinical cure?

1. What is clinical cure of hepatitis B?

First of all, we need to clarify what is clinical cure of hepatitis B. Generally speaking, clinical cure of hepatitis B refers to the disappearance of the patient's hepatitis B surface antigen (HBsAg), with or without hepatitis B surface antigen (HBsAg).AntibodyWith the emergence of anti-HBs, serum hepatitis B virus (HBV) DNA is undetectable, liver function is normal, and liver histological lesions are improved.

2. Factors affecting recurrence

Well, after achieving clinical cure, the possibility of recurrence exists, but it is relatively low. There are many factors that affect recurrence, which are introduced in detail below:

1. Individual immune status: The immune system plays a key role in controlling the hepatitis B virus. If the patient's immune system is weak and cannot effectively suppress the virus continuously, it may lead to the reactivation of the virus and increase the risk of recurrence.

For example, some patients who suffer from other chronic diseases, use immunosuppressants for a long time, or have impaired immune function may have a relatively high chance of recurrence.

2. Treatment plan and course of treatment: Different treatment methods and duration of treatment will also affect the probability of recurrence. If the treatment is not thorough or the course of treatment is insufficient, the residual virus may replicate again under suitable conditions.

Just like some patients do not strictly follow the doctor's instructions during the treatment process and stop or reduce the medication on their own, this may lay the hidden danger of recurrence.

3. Lifestyle and habits: Bad living habits, such as long-term alcoholism, overwork, frequent staying up late, etc., may weaken the body's resistance, increase the burden on the liver, and create conditions for the recurrence of hepatitis B virus.

3. How to reduce the recurrence of hepatitis B?

In order to reduce the risk of recurrence after clinical cure of hepatitis B, patients need to do the following:

1. Regular follow-up examination: This is a crucial step. Patients are advised to undergo hepatitis B virus markers, liver function, liver ultrasound and other examinations every 3-6 months within one year after recovery. The follow-up interval can be appropriately extended based on the doctor's advice.

2. Maintain a healthy lifestyle: eat a balanced diet, exercise moderately, quit smoking and limit alcohol, and ensure adequate sleep to enhance your immunity.

3. Avoid factors that may damage the liver: Try to avoid using medications that may damage the liver and avoid contact with toxic and harmful substances.

In short, clinical cure of hepatitis B is an important stage victory, but patients should not take it lightly. Through active preventive measures and regular monitoring, we can minimize the risk of recurrence and maintain a healthy state for a long time.